Neurological Glossary

Neurological terms are often complicated and difficult to understand. The following glossary defines a variety of terms to help you understand neurological terminology:

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Lacunar stroke/ lacunar infarct

A small stroke affecting an area of tissue less than one centimetre in diameter

    Lateral

    Further from the midline

      Lambert-Eaton Myasthenic syndrome

      Autoimmune disorder of neuromuscular transmission characterised by antibodies directed against the voltage-gated calcium channels on the presynaptic motor nerve terminal leading to impaired release of acetylcholine and causing proximal muscle weakness

        Laminar necrosis

        Selective neuronal loss in layers 3 and 5 of the cerebral cortex due to hypoxic-ischemic insult

          Lateral medullary syndrome (Wallenberg's syndrome)

          Constellation of symptoms including difficulty swallowing

            LD

            Learning Difficulties

              LDL (Low Density Lipoprotein)

              The source of waxy plaque on the artery walls. LDL is usually called bad cholesterol

                Left hemisphere

                The brain has two sides to it

                  Lennox-Gastaut syndrome

                  Syndrome of mental retardation

                    Lentiform nucleus (lenticular nucleus)

                    Lens-shaped part of the basal ganglia consisting of the putamen and globus pallidus

                      Leptomeninges

                      Arachnoid mater and pia mater

                        Lethargy

                        A state of sluggishness

                          Leukodystrophy

                          Metabolic demyelinative disease

                            Lewy body

                            Cytoplasmic

                              Lewy body dementia

                              Type of dementia that is caused by small proteins that form on the nerve cells in the brain disrupting memory and motor control. It can also cause changes in attention

                                Light-near dissociation

                                Absent pupillary light response but intact near response (i.e.

                                  Limbic

                                  Referring to the system comprising the hippocampus

                                    Lipohyalinosis

                                    Eosinophilic deposits in the connective tissue of the walls of perforating arterioles in the deep portions of the brain due to hypertension; contributes to the development of lacunar infarction and hypertensive hemorrhage

                                      Lipoproteins

                                      Cholesterol travels though the blood through different compounds called lipoproteins

                                        Lissauer's tract

                                        Longitudinal bundle of thin

                                          Lissencephaly (agyria)

                                          Smooth brain (absence of secondary sulci)

                                            Lobe

                                            One of four major portions of the cerebral cortex named after the overlying cranial bones: frontal

                                              Locked-in state

                                              Tetraplegia and aphonia with preserved consciousness due to brainstem (usually pontine) lesion that spares the reticular activating system

                                                Locus ceruleus

                                                Melatonin-containing nucleus located on the dorsal wall of the upper Pons that is one of the main sources of neuroepinepherine in the brain and has widespread projections to other parts of the nervous system; mediates arousal and primes neurons throughout the nervous system to be activated by stimuli

                                                  Loftstrand Crutch

                                                  Type of crutch with an attached holder for the forearm that provides extra support

                                                    Long-tract signs

                                                    Signs referable to the corticospinal tract

                                                      Lordosis

                                                      Exaggerated hollow in the lower back

                                                        Lower motor neuron

                                                        Second order neurons whose cell bodies are located in the brainstem or anterior horn of the spinal cord and that leave the CNS to connect to muscle; lesions result in flaccid weakness

                                                          Lumbar Puncture

                                                          A procedure whereby some of the spinal fluid is removed by the insertion of a needle into the spine

                                                            Lycra splint

                                                            A material suit that supports the body while allowing function